T/CALAS 98-2020 Experimental animal Technical specification for preparation of animal model for COVID-19 (coronavirus disease)
T/CALAS 98-2020 Experimental animal Technical specification for preparation of animal model for COVID-19 (coronavirus disease)
Basic Information
Scope
Scope: This document specifies the technical requirements for risk control, personnel training, animal quality control, animal anesthesia, animal infection, model symptom observation, model biochemical indicator detection, model viral load determination, and serum antibody detection during the preparation of animal models for COVID-19. This document is applicable to the preparation and evaluation of animal models for COVID-19, including rodents and non-human primates. Main technical contents: Scope, normative reference documents, terms and definitions, risk control requirements, personnel training requirements, animal quality control requirements, anesthesia operation requirements, COVID-19 animal model infection technical requirements, general symptom observation requirements for COVID-19 rodent models, general symptom observation requirements for COVID-19 rhesus monkey models, COVID-19 animal model blood biochemical detection requirements, specimen viral load detection operation requirements, serum IgG antibody titer detection technical requirements, and neutralizing antibody detection technical requirements.