T/CACM 012-2017 Guidelines for the Clinical Practice of Using Traditional Chinese Medicine Monotherapy/Combination with Antibiotics in the Treatment of Common Infectious Diseases: Septicemia

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Main technical content: While antibiotics play an active role in the treatment of sepsis, their misuse and the resulting drug-resistant bacterial infections have become a global concern. Sepsis is one of the major complications in the development of various infectious diseases, and bacterial infections are the main factors leading to sepsis. It is estimated that approximately 5.3 million patients die from sepsis each year, with most deaths caused by multiple organ and systemic damage caused by multidrug-resistant bacterial infections. Therefore, antibiotic treatment is an important step in reducing the mortality rate of sepsis, and antibiotics play an irreplaceable role in the treatment of sepsis. During antibiotic treatment, the use of traditional Chinese medicine can first enhance the antibacterial and bactericidal effects of antibiotics, and it also has certain bactericidal capabilities itself. Secondly, it also has certain advantages in preventing and treating drug-resistant bacteria. At the same time, in the treatment of sepsis, traditional Chinese medicine plays an important role in restoring the patient's immune function and repairing the inflammatory response. Due to the high incidence and mortality of sepsis, traditional Chinese medicine supplementing antibiotic treatment for sepsis has certain advantages, which to some extent solves the problem of drug resistance in sepsis, so it is very necessary to formulate relevant guidelines. At present, there are no guidelines or expert consensus on the use of traditional Chinese medicine to supplement antibiotic treatment for sepsis. This guideline, based on the methods and processes of international clinical practice guidelines, guided by relevant laws and regulations and technical documents, based on the best available evidence and fully combining expert experience and patient preferences, combined with the characteristics of traditional Chinese medicine itself and clinical actual situations, formulates clinical p

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