T/SXQCA 006-2024 The Fireworks and Explosives Toxicity Evaluation Specification: Skin Sensitization Substitute Test
T/SXQCA 006-2024 The Fireworks and Explosives Toxicity Evaluation Specification: Skin Sensitization Substitute Test
Basic Information
Scope
Scope: This document provides general toxicity test methods and selection strategies for explosives. This document specifies the principles, reagents, instruments, test procedures, result evaluation, and test reports for in vitro skin sensitization testing of flammable, explosive, toxic, and hazardous materials in the explosives industry. This document is applicable to evaluating the skin sensitization of explosives using the luciferase assay and human cell line activation assays. Main technical content: The "Explosives Toxicity Evaluation Guidelines - Skin Sensitization Alternative Testing" standard describes the evaluation method of small-dose explosives skin sensitization alternative testing, and applies the luciferase assay and human cell line activation assay methods to evaluate the skin sensitization of explosives. The main technical content includes scope, normative reference documents, terms and definitions, test principles, reagents, instruments, test procedures, and results, etc.