T/COCIA 58-2026 The determination method for orally administered oral cleaning products containing orlaflur method for the determination of ethoxylated N-oil-based-1,3-propanediamine and its hydrogen fluoride compound, ethoxylated N-palm-based-1,3-propanediamine and its hydrogen fluoride compound, and ethoxylated N-stearic acid-based-1,3-propanediamine and its hydrogen fluoride compound

Scope

This document specifies the detection methods for ethoxylated N-oleyl-1,3-propanediamine and its hydrofluoride, ethoxylated N-palmitoyl-1,3-propanediamine and its hydrofluoride, and ethoxylated N-stearoyl-1,3-propanediamine and its hydrofluoride in oral care products containing orofluoride, including high-performance liquid chromatography-evaporative light scattering and high-performance liquid chromatography-tandem mass spectrometry. It specifically includes the principles of the test method, reagents and materials, instruments and equipment, analysis steps, result calculation, detection limit and quantitative limit, recovery rate and precision, as well as allowable deviations. This document is applicable to the qualitative and quantitative detection of the main components of orofluoride in oral care products such as toothpaste, mouthwash, oral spray, and tooth powder that contain orofluoride.

Development Information

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