T/BPSPA 0016-2022 Natural folic acid (6S-5-methyltetrahydrofolate calcium)
T/BPSPA 0016-2022 Natural folic acid (6S-5-methyltetrahydrofolate calcium)
Basic Information
Scope
Scope: This document specifies the requirements for the process, raw materials, sensory properties, physical and chemical properties, microbiological quality, net content and allowable shortage of natural folic acid, as well as the production environment. It describes the corresponding inspection methods, stipulates the inspection rules, marking, labeling, packaging, transportation, and storage requirements, and provides information on the chemical name, molecular formula, structural formula, and relative molecular mass of natural folic acid. This document applies to the production, inspection, and sale of natural folic acid (6S-5-methyltetrahydrofolic acid calcium) prepared from folic acid and calcium chloride through reduction, cyclization, fractionation, and salt formation processes. Main technical content: Natural folic acid is a product obtained from folic acid and calcium chloride through reduction, cyclization, fractionation, and salt formation processes, which meets or approaches the safety level of natural folic acid. It is an upgraded version of active folic acid. (Note 1: Natural folic acid, also known as dietary folic acid, is mainly composed of 6S-5-methyltetrahydrofolic acid and is mainly found in liver, grains, legumes, dark green leafy vegetables, oranges, and eggs. Note 2: Active folic acid is the active form of folic acid that does not require metabolism and can be directly absorbed and utilized by the human body.) This standard is based on existing national standards for folic acid, the announcement of the National Health Commission on 6S-5-methyltetrahydrofolic acid calcium, and international standards, management, and detection methods for folic acid. It specifies the requirements for the process, raw materials, sensory properties, physical and chemical properties, microbiological quality, net content and allowable shortage of natural folic acid, as well as the production environment. It describes the corresponding inspection methods, stipulat