T/CSB 0005.2-2024 Organ Chip Hepatic Part 2: Model Function Detection Specification

Scope

Main technical content: Organ-on-a-chip is a new type of technology and tool platform developed in recent years in the field of biomedicine. It integrates engineering and biological strategies and can simulate the key structures and functional characteristics of human tissues and organs in vitro. It is a novel model for human physiological and pathological research and has broad application prospects in life sciences, disease mechanisms, environmental exposure, toxicology research, and new drug development. At present, the development of the organ-on-a-chip field is at a critical stage. On the one hand, the technology is constantly being updated and the application space continues to expand; on the other hand, as a new type of non-clinical testing method, the common and characteristic elements of organ-on-a-chip, such as the classification and definition of organ-on-a-chip, structural design, cell sources, preparation processes, model construction, and functional verification, still lack consistent standards, becoming a bottleneck for the industrialization and promotion of organ-on-a-chip. In view of this, the formulation of the "Organ-on-a-Chip Liver" group standard aims to promote and guide research related to the construction and application of liver chip models, standardize and guide their transformation and application, and provide a basis for scientific supervision. This group standard includes two parts: "Organ-on-a-Chip Liver Part 1: Model Construction Standards" and "Organ-on-a-Chip Liver Part 2: Model Function Detection Standards".

Development Information

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