T/CACM 1318.21-2019 Digestive system common diseases: Chinese medicine guideline for diagnosis and treatment, Part 21: Functional diarrhea (basic medical doctor edition)

Scope

Main technical content: Functional diarrhea is a common disease of the digestive system, the pathogenesis of which is still unclear. Currently, it is believed that it may be related to the increased intestinal motility caused by the patient's diet and emotions. Therefore, in the treatment of functional diarrhea, Western medicine generally uses conventional anti-diarrheal drugs, such as loperamide and benztropine, in addition to relieving the patient's anxiety and controlling the triggering factors. These drugs work by binding to opioid receptors to prevent cholinergic nerve endings from releasing acetylcholine, thereby exerting an anti-diarrheal effect. However, clinical use of these drugs often leads to side effects such as constipation, bloating, and abdominal pain. In addition, adsorbents, antibiotics, and probiotics are also used to treat functional diarrhea, but there is a high recurrence rate after discontinuing medication. Traditional Chinese medicine (TCM) has proven effective in treating functional diarrhea and can greatly alleviate or avoid the side effects of constipation, abdominal pain, and bloating caused by Western anti-diarrheal drugs, as well as drug dependence. However, there are currently no standardized guidelines for the treatment of functional diarrhea with TCM, and it is particularly important to develop relevant standardized guidelines. This guideline follows the methods and processes of international clinical practice guidelines, and under the guidance of relevant laws, regulations, and technical documents, it is based on the best available evidence and fully integrates the clinical experts' experience and patients' wishes to develop a TCM diagnosis and treatment guideline for functional diarrhea, guiding the clinical standardized use of TCM, reducing the side effects of conventional anti-diarrheal treatment, and improving clinical efficacy.

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