T/BYXT 057-2024 Coated rare earth phosphate fluorescent nano-materials

Scope

Scope: This document specifies the terms and definitions, classification, raw material requirements, production requirements, process requirements, technical requirements, test methods, inspection rules, marking, packaging, transportation, and storage of coated rare earth phosphate fluorescent nanomaterials. This document applies to coated rare earth phosphate fluorescent nanomaterials. The products specified in this document are suitable for use in the biological and medical fields as fluorescent markers, photothermal therapy, drug carriers, immunoassays, biochips, detection of bacteria and microorganisms in food and the environment, and optical biological imaging, etc. Main technical contents: 8.1 Sensory requirements: Sensory requirements shall comply with the provisions of Table 1. Table 1 Sensory requirements: Indicators and testing methods. Appearance: White, loose, solid, powder. Visual inspection. Microscopic morphology: Uniform core-shell structure of nanoparticles. Field emission scanning electron microscopy and transmission electron microscopy testing. 8.2 Physical and chemical requirements: Physical and chemical requirements shall comply with the provisions of Table 2. Table 2 Physical and chemical requirements: Indicators. PEG-coated type E2 Chitosan-coated type E3 Average particle size/nm D50≤60 D90≤80 Loose density/g/cm3 3.6±0.5 3.0±0.5 Coating thickness/nm 5-10 5-10 Water soluble time (0.01g/L)/s 4-10 4-10 Spectral performance: Excitation wavelength range/nm 200-450 Emission peak wavelength range/nm 400-800 400-800 Net content/kg Marked net weight ±0.1

Development Information

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