GB/T 15000.3-2008 Directives for the work of reference materials(3)—Reference materials—General and statistical principles for certification
GB/T 15000.3-2008 Directives for the work of reference materials(3)—Reference materials—General and statistical principles for certification
Basic Information
Scope
The statistical principles presented in this section aim to assist in understanding and developing effective methods for assigning values to the characteristics of standard samples, including methods for evaluating uncertainties and establishing measurement traceability. Standard samples (RMs) produced in accordance with all the steps described in this section are typically accompanied by certificates and are referred to as certified reference materials (CRMs). This section will help to fully exploit the potential of CRMs to ensure the comparability, accuracy, and consistency of measurement results at the national or international level. To be comparable in time and space, measurements need to be traced back to appropriate and defined measurement standards. In chemistry, biology, and physics, especially in disciplines involving materials and/or samples, CRMs play an important role in establishing the traceability of measurement results. Laboratories use CRMs as easily accessible measurement standards to trace their measurement results back to international standards. During the production of CRMs, their characteristic values can be traced back to SI units or other units defined by international agreements. This section explains how to develop methods that can accurately determine characteristic values and trace them back to appropriate and defined measurement standards. This section applies to a wide range of materials (matrices), from mixed gases to biological samples, as well as to various characteristics, from chemical compositions to physical and immunological testing properties. The methods described in this section are not necessarily applicable to all aspects of CRM production and the determination of characteristic values (including uncertainties). The methods presented in this section can be considered as the main approach for most CRM production and value assignment, although some special cases may require appropriate modifications. The statistical metho