T/CQCAA 0009-2021 Active Group standards

T/CQCAA 0009-2021 Determination of 14 whitening active ingredients in cosmetics by liquid chromatography-mass spectrometry

Publish Date: 2021-12-07 Implement Date: 2022-01-05 For services related to genuine standard inquiry, procurement, translation, and other related services in China, please Contact Us

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Basic Information

Standard Code: T/CQCAA 0009-2021

Standard Type: Group standards

Standard Status: Active

is_force_gb: no

CCS Name: Daily chemical products

ICS Name: Chemical analysis

Publish Date: 2021-12-07

Implement Date: 2022-01-05

Scope

Main technical content: The "Determination of 14 Whitening Active Ingredients in Cosmetics by Liquid Chromatography-Mass Spectrometry" takes whitening and spot-removing cosmetics as the research object. The whitening ingredients include L-(+)-tartaric acid, magnesium ascorbyl phosphate, L-(-)-malic acid, ascorbic acid glucoside, L-(+)-lactic acid, citric acid, niacinamide, ascorbyl palmitate, glycolic acid, kojic acid, β-arbutin, raspberry glycoside, nonanoic acid, and 4-methoxysalicylic acid potassium. The extraction solvent used is potassium dihydrogen phosphate solution, and the pretreatment technology of HLB solid-phase extraction cartridges is adopted. Combined with liquid chromatography-mass spectrometry analysis, the analysis and detection technology of 14 whitening ingredients is established. The target substances are completely separated in 10 minutes, and the detection limit range is 0.000007%~0.00025% (0.070~2.5mg/kg), and the quantification limit range of the samples is 0.00002%~0.00075% (0.20~7.5mg/kg). This method improves the accuracy and sensitivity of the detection results, effectively avoids the occurrence of false negative and false positive results in the actual sample detection process, and provides technical support and reliable data support for the supervision and detection of whitening ingredients in cosmetics.