T/SXQCA 008-2024 Fireworks and Explosives Toxicity Evaluation Standards: Genetic Toxicity Test
T/SXQCA 008-2024 Fireworks and Explosives Toxicity Evaluation Standards: Genetic Toxicity Test
Basic Information
Scope
Scope: This document specifies the in vivo and in vitro test methods and selection strategies for the genetic toxicity of explosives. This document is applicable to the evaluation of the genetic toxicity of explosives and energetic materials; Main technical content: The standard "Explosives Toxicity Evaluation Guidelines - Genetic Toxicity Testing" specifies the optimal combination and selection strategies for in vivo and in vitro genetic toxicity testing of explosives. The main technical content includes scope, normative reference documents, terms and definitions, and optimization combinations for genetic toxicity testing, describing methods such as bacterial reverse mutation tests, in vitro mammalian cell gene mutation tests, in vitro mammalian cell chromosome aberration tests, and mammalian erythrocyte micronucleus tests.