T/SDAA 0085-2024 The safety evaluation procedures for environmental modification of Escherichia coli and Salmonella phages used in animal husbandry
T/SDAA 0085-2024 The safety evaluation procedures for environmental modification of Escherichia coli and Salmonella phages used in animal husbandry
Basic Information
Scope
Main technical content: Scope: Evaluation of the safety, antibacterial performance, and quality control of ecological improvement agents for Escherichia coli and Salmonella phages in laboratory and veterinary clinical settings. Main technical content: ① Gene environment: Screening for toxin genes, drug resistance genes, and integrase genes to prevent the spread and integration of harmful genes; ② In vitro antibacterial performance: Including titer, lysis spectrum, lysis rate, lysis potency, optimal infection multiplicity, optimal antibacterial ratio, antibacterial time, and synergistic antibacterial combinations; ③ Biological properties: Including one-step growth curves, temperature and pH stability; ④ Presence or absence of residual production strains or other contaminating bacteria.