T/JSQGXH 001-2026 Active Group standards

T/JSQGXH 001-2026 Technical code of practice for screening of estrogens in water-based cosmetics —Transgenic fluorescent zebrafish embryo method

Publish Date: 2026-04-13 Implement Date: 2026-04-13 For services related to genuine standard inquiry, procurement, translation, and other related services in China, please Contact Us

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Basic Information

Standard Code: T/JSQGXH 001-2026

Standard Type: Group standards

Standard Status: Active

is_force_gb: no

CCS Name: -

ICS Name: Cosmetics and beauty products

Publish Date: 2026-04-13

Implement Date: 2026-04-13

Scope

This document describes a method for screening estrogen in water-based cosmetics using Tg(5×ERE:EGFP) transgenic fluorescent zebrafish embryos. This document is applicable to the screening of estrogen in liquid water-based, gel-based, and emulsion-based cosmetics. This standard is applicable to the screening of estrogen in water-based cosmetics, and it specifies the detection technology based on the transgenic fluorescent zebrafish model. The core content includes: defining key terms, clarifying the cultivation and quality control requirements of the transgenic fluorescent zebrafish model; explaining the detection principle, that is, estrogen activates the receptor to initiate fluorescent protein expression, and the fluorescence intensity is used to determine the presence of estrogen; stipulating the steps of sample collection, pretreatment, exposure experiment, fluorescence detection, and result determination methods. The methodological validation shows that the model has good stability and specificity, is applicable to a variety of water-based cosmetics, and the detection limits of some estrogens are comparable to those of traditional instrument methods. It fills the gap in existing detection technologies and provides technical support for supervision.