T/GDCA 055-2025 Determination of dipeptide d-diaminobutyric acid benzylamide diethylacetate, acetyl hexapeptide-8, acetyl octapeptide-3, and palmitoyl tripeptide-5 using high performance liquid chromatography-tandem mass spectrometry
T/GDCA 055-2025 Determination of dipeptide d-diaminobutyric acid benzylamide diethylacetate, acetyl hexapeptide-8, acetyl octapeptide-3, and palmitoyl tripeptide-5 using high performance liquid chromatography-tandem mass spectrometry
Basic Information
Scope
Scope: This document is applicable to the detection of dipeptide diamino butylamide diacetate, acetyl hexapeptide-8, acetyl octapeptide-3, and palmitoyl tripeptide-5 in cosmetic raw materials and finished products. This method has a detection limit of 1 μg/L and a quantification limit of 5 μg/L for dipeptide diamino butylamide diacetate; a detection limit of 0.5 μg/L and a quantification limit of 1.5 μg/L for acetyl hexapeptide-8; a detection limit of 0.5 μg/L and a quantification limit of 1.5 μg/L for acetyl octapeptide-3; and a detection limit of 0.5 μg/L and a quantification limit of 1.5 μg/L for palmitoyl tripeptide-5. Main technical content: Introduction 1 Scope 2 Normative references 3 Terms and definitions 4 Principle 5 Reagents and materials 6 Instruments and equipment 7 Test steps 8 Result calculation and expression 9 Detection and quantification limits 10 Recovery and precision 11 Permissible deviations Appendix A (informative) Chemical name, molecular formula, structural formula, relative molecular mass, and CAS number Appendix B (informative) Total ion chromatogram (TIC) of standard solutions of dipeptide diamino butylamide diacetate, acetyl hexapeptide-8, acetyl octapeptide-3, and palmitoyl tripeptide-5 References