T/CBJ 1109-2025 Evaluation method for alcohol metabolic rate in blood after drinking beverages
T/CBJ 1109-2025 Evaluation method for alcohol metabolic rate in blood after drinking beverages
Basic Information
Scope
This document specifies the principles, reagents and materials, experimental procedures, and evaluation of alcohol metabolism rates after drinking beverage alcohol. This document is applicable to experiments using model animals (rats and mice) that consume the same type of beverage alcohol with the same alcohol concentration (within 1% vol) and evaluate the alcohol metabolism rates after drinking. To ensure the operability of the experimental method, the experimental groups are divided based on alcohol concentration. This document specifies the principles, reagents and materials, experimental procedures, and evaluation of alcohol metabolism rates after drinking beverage alcohol. This document is applicable to experiments using model animals (rats and mice) that consume the same type of beverage alcohol with the same alcohol concentration (within 1% vol) and evaluate the alcohol metabolism rates after drinking. To ensure the operability of the experimental method, the experimental groups are divided based on alcohol concentration. Principle Model animals (mice and rats) are easy to obtain, simple to handle, and can strictly control experimental conditions. They also have high accuracy of results, good repeatability, and strong comparability, making them commonly used in alcohol metabolism evaluation research. By giving model animals (mice and rats) an appropriate dose of beverage alcohol, the blood ethanol concentration at key time points after drinking is analyzed using headspace-gas chromatography, and the decrease in blood ethanol concentration per unit time during the sampling interval is calculated to obtain the alcohol metabolism rate after drinking beverage alcohol.