YY/T 0688.1-2023 Active
YY/T 0688.1-2023 Susceptibility testing of infectious agents and evaluation of performance of antimicrobial susceptibility test devices—Part 1:Broth micro-dilution reference method for testing the in vitro activity of antimicrobial agents against rapidly growing aerobic bacteria involved in infectious diseases
Abstract
This document describes a reference method for determining the MIC values of antimicrobial drugs—the broth microdilution method. The MIC values can serve as a guide for doctors, reflecting the antibacterial activity of antimicrobial drugs under specified in vitro test conditions. Other factors such as drug pharmacology, pharmacokinetics, or bacterial resistance mechanisms should also be considered. This allows bacteria to be classified as "sensitive (S)", "intermediate (I)", or "resistant (R)". Additionally, the distribution of MIC values can be used to identify wild-type or non-wild-type bacterial populations. Although the clinical interpretation of MIC values is beyond the scope of this document, it is necessary to adjust the basic methods for certain antimicrobial drug-bacteria combinations to facilitate clinical interpretation. These adjustments are included in a separate appendix of this document. To ensure the comparability and reliability of test results, it is necessary to validate other antimicrobial susceptibility test methods (such as the disk diffusion method or diagnostic test devices) against this reference method.
This document is applicable to determining MIC values using the broth microdilution method.
General Product Information
| Document Type | Industry standards-Medicine |
|---|---|
| Standard Status | Active |
| Standard Code | YY/T 0688.1-2023 |
| CCS | Medical devices |
| ICS | Laboratory medicine |
| Implement Date | 2023-11-01 |