GB/T 46249-2025 Chemicals—Rapid androgen disruption activity reporter(RADAR) assay
GB/T 46249-2025 Chemicals—Rapid androgen disruption activity reporter(RADAR) assay
Basic Information
Scope
This document describes the experimental methods for rapid androgenic interference activity reports of chemicals.
This document is suitable for testing and evaluating the androgenic interference activity of test substances, used to determine the fluorescence intensity of test substances in embryos of the transgenic Japanese medaka (Oryzias latipes) containing the spg1-gfp gene; it is also suitable for all non-volatile or low-volatile test substances that can be accurately measured.
This document is not suitable for volatile test substances.
Note: If used to test mixtures, unknown complex substances (UVCB) or multi-component substances, the components should be characterized, such as their chemical properties, quantitative status, and material properties.