T/CXDYJ 0003-2023 Antioxidant micronutrient premixes for microencapsulation and production of nano-formulations technical regulations

Scope

Scope: This document specifies the production environment and equipment requirements, formulation composition and requirements, production technology process, quality inspection, storage and transportation, and production records for microencapsulated nano-formulations of antioxidant micronutrient premixes in the production of elderly food products. This document applies to the production of microencapsulated nano-formulations of antioxidant micronutrient premixes (hereinafter referred to as "formulations") for elderly food products; Main technical content: - Production technology process: 1. Dissolution: Add curcumin and soy isoflavones, a small amount of soy lecithin, and food-grade ethanol to a mixing tank with stirring function. Stir for more than 5 minutes until the raw materials are completely dissolved and dispersed. After removing the ethanol, a curcumin, soy isoflavone, and soy lecithin complex is obtained. Glucosamine, L-carnitine, anthocyanins, and proanthocyanidins are dissolved in purified water according to the mass fraction in Table 1 and prepared into aqueous solutions at room temperature in a ratio of 1:5-10. 2. Phospholipid complexation: Add plant sterols, lutein, and lycopene to rapeseed oil (first extraction grade) at a dissolution temperature of 40-50°C and a dissolution ratio of 0.4-1.3%. 3. First high-pressure homogenization: Add the mixtures obtained in 6.2.1-6.2.3, soy lecithin, and sorbitol to a high-pressure homogenizer, supplement with purified water to 100%, and introduce nitrogen gas at a flow rate of 1 L/min. Homogenize under a pressure of 5 MPa at a temperature of 30°C for 20 minutes to obtain a homogenized solution. 4. Second high-pressure homogenization: Place the homogenized solution obtained in 6.3 into a high-pressure homogenizer again, introduce nitrogen gas at a flow rate of 1 L/min, and nano-process at a pressure of 100 MPa for 7 times to obtain a liposomal liquid; wherein the diameter of the liposomes is 300-500 nm,

Development Information

Related Standards