T/QMIS 003-2022 Determination of Quinolone Drugs in Seawater by Liquid Chromatography-Tandem Mass Spectrometry
T/QMIS 003-2022 Determination of Quinolone Drugs in Seawater by Liquid Chromatography-Tandem Mass Spectrometry
Basic Information
Scope
Main technical content: This method specifies the sampling, processing, analysis steps, result calculation, quality assurance, and quality control methods and procedures for determining the residual amounts of 17 quinolone drugs in seawater by high-performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS). This method is suitable for determining the residual amounts of enoxacin, marbofloxacin, ofloxacin, pefloxacin, florfenicol, lomefloxacin, norfloxacin, ciprofloxacin, orbifloxacin, enrofloxacin, danofloxacin, sarafloxacin, sparfloxacin, difloxacin, oxolinic acid, and florfenicol in seawater, either individually or in combination. The detection limit for quinolone drugs in seawater is 5.0 ng/L, and the quantification limit is 20 ng/L.