GB/Z 39262-2020 Nanotechnologies—Guidance on toxicological screening methods for nanomaterials

Scope

This guidance technical document provides methods for in vitro and in vivo toxicological and ecotoxicological screening tests suitable for nanomaterials. These methods are helpful for screening the toxicology, including ecotoxicology, of nanomaterials. The toxicological screening tests in this guidance technical document can be used for early judgment in research and product development, providing rapid feedback on potential toxicological/safety risks, or conducting preliminary evaluations. This guidance technical document can be divided into toxicological screening methods related to human health and those related to the environment. Screening tests refer to relatively simple and inexpensive methods that are easy to conduct and can provide corresponding indications of whether nanomaterials have potential negative effects on humans and the environment.
This guidance technical document focuses on describing preliminary screening methods suitable for toxicological evaluation, which complements other foreign standards and does not duplicate relevant documents of other international organizations such as the OECD. If the screening results indicate early indications of harm, this guidance technical document will guide testers to refer to the documents of other organizations for comprehensive toxicological evaluation or further comprehensive research.

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